Flow-Induced Vibration Hybrid Modeling Method and Dynamic Characteristics of U-Section Rubber Outer Windshield System of High-Speed Trains

The flow-induced vibration characteristic of the U-section rubber outer windshield structure of high-speed train is the key factor to limit its high-speed movement.Accurate and effective flow-induced vibration analysis of windshield structures is an important topic.In this paper, a hybrid modeling method for the analysis of flow-induced vibration o

read more

Proteomic and immunoproteomic characterization of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae

Abstract Background Protection of pigs by vaccination against Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is hampered by the presence of 15 different serotypes.A DIVA subunit vaccine comprised of detergent-released proteins from A.pleuropneumoniae serotypes 1, 2 and 5 has been developed and shown to protect pigs

read more

Eliciting an immune-mediated antitumor response through oncolytic herpes simplex virus-based shared antigen expression in tumors resistant to viroimmunotherapy

Background Oncolytic virotherapy (OV) is an immunotherapy that incorporates viral cancer cell lysis with engagement of the recruited immune response against cancer cells.Pediatric solid tumors are challenging targets because they contain both an inert immune environment and a quiet antigenic landscape, making them more resistant to conventional OV

read more